Sodium trifluoromethanesulfinate Chemical Properties

Melting point:

<325°C

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

Water (Sparingly)

form 

powder

color 

white

BRN 

3723394

InChI

InChI=1S/CHF3O2S.Na.H/c2-1(3,4)7(5)6;;/h(H,5,6);;

InChIKey

KAVUKAXLXGRUCD-UHFFFAOYSA-M

SMILES

C(F)(F)(F)S(O)=O.[NaH]

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38-36/38

Safety Statements 

26-36/37/39

WGK Germany 

3

TSCA 

No

HazardClass 

IRRITANT

HS Code 

29309090

Sodium trifluoromethanesulfinate Usage And Synthesis

Chemical Properties

White to light yellow solid

Uses

Efficient sulfinate salt for the trifluoromethylation of various aryls, aryl boronic acids, alkenes, and alkynes.

Uses

Sodium Triflinate (Sodium trifluoromethanesulfinate), is a sulfur-containing building block and Fluorination reagents, used in various organic synthesis. It can be used in a new and convenient method for the copper-catalyzed construction of functional sulfonamides in good yields and excellent chemoselectivity.

reaction suitability

reaction type: C-C Bond Formation

Solubility in water

soluble in H2O, slightly soluble in MeOH, MeCN, and acetone.

Synthesis

At first, an aqueous solution was prepared by dissolving 37.5 g of sodium sulfite in 150 g of water. Then, a metal pressure-proof reactor was charged with this aqueous solution. After that, the atmosphere of the reactor was removed to obtain a reduced pressure. 10.7 g of trifluoromethanesulfonic fluoride was added to the reactor, stirring at 5° C. for 4 hr. The resulting reaction liquid was neutralized with sodium carbonate, followed by water removal. Then, methanol was added to the remaining solid matter to extract the target product. The resulting methanol solution was concentrated to dryness, thereby obtaining 9.7 g of sodium trifluoromethanesulfinate (yield: 88%).

References

[1] Patent: US2001/31891, 2001, A1
[2] Patent: US2001/31891, 2001, A1

Sodium trifluoromethanesulfinate(2926-29-6)Related Product Information

• Sodium bicarbonate
• Sodium p-toluenesulfinate
• Sodium methanesulfinate
• 1-DODECANESULFONIC ACID SODIUM SALT
• Formaldehyde sodium bisulfite
• Sodium chloride
• BENZENESULFINIC ACID SODIUM SALT
• Sodium trifluoromethanesulfonate
• Sodium acetate
• Trifluoromethyl iodide
• Sodium formate
• 2-METHYL-2-PROPENE-1-SULFONIC ACID SODIUM SALT
• 2-(Trifluoromethyl)benzoic acid
• Sodium carbonate
• Sodium gluconate
• Sodium hydroxide
• Trifluoromethanesulfonic acid
• Diclofenac sodium