RS 102221 HYDROCHLORIDE
RS 102221 HYDROCHLORIDE Basic information
- Product Name:
- RS 102221 HYDROCHLORIDE
- Synonyms:
-
- RS 102221 HYDROCHLORIDE
- 8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulfonamido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dionehy
- RS102221HCl
- 8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulfonamido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.
- 8-[5-(2,4-Dimethoxy-5-(4-Trifluoromethylphenylsulphonamido)Phenyl-5-Oxopentyl)]-1,3,8-Triazaspiro[4.5]Decane-2,4-Dione Hydrochloride
- 8-[5-(2,4-DIMETHOXY-5-(4-TRIFLUOROMETHYLPHENYLSULPHONAMIDO)PHENYL-5-OXOPENTYL)]-1,3,8-TRIAZASPIRO[4.5]DECANE-2,4-DIONE HYDROCHLORIDE
- N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide
- RS 102221
- CAS:
- 185376-97-0
- MF:
- C27H31F3N4O7S
- MW:
- 612.62
- Mol File:
- 185376-97-0.mol
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RS 102221 HYDROCHLORIDE Chemical Properties
- Density
- 1.45
- storage temp.
- Store at RT
- solubility
- DMSO: ≥20mg/mL
- form
- powder
- color
- white
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RS 102221 HYDROCHLORIDE Usage And Synthesis
Uses
RS 102221 Hydrochloride is a selective 5-HT2C receptor antagonist.
Definition
ChEBI: N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide is an aromatic ketone.
Biological Activity
Potent and selective 5-HT 2C antagonist (pK i = 8.7). Displays ~ 100-fold selectivity over the 5-HT 2A and 5-HT 2B subtypes and is > 100-fold selective over other 5-HT receptors, a- and b-adrenergic and muscarinic ACh receptors.
RS 102221 HYDROCHLORIDESupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
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- 821-50328103-801 18930552037
- 3bsc@sina.com
LETOPHARM LIMITED
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- +86-21-5821 5861
- sales@letopharm.com
Tianjin Kailiqi Biotechnology Co., Ltd.
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- 15076683720
- klq@cw-bio.com
Amatek Scientific Co. Ltd.
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- 0512-56316828
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Jinan ponder chemical co. LTD
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- 0531-0000
- thinklifescience@163.com