Octahydroaminoacridine Chemical Properties

form 

Solid

color 

White to off-white

InChI

InChI=1S/C13H17N9/c14-4-2-1-3-5(15)7(17)9(19)11(21)13(3)22-12(2)10(20)8(18)6(4)16/h1H,14-21H2

InChIKey

OAOMMMVMPIWKGM-UHFFFAOYSA-N

SMILES

C1(N)=C2C(N=C3C(=C2)C(N)=C(N)C(N)=C3N)=C(N)C(N)=C1N

Octahydroaminoacridine Usage And Synthesis

Uses

Octahydroaminoacridine succinate, a Tacrine analogue, is an acetylcholinesterse (AChE) and butyrylcholinesterase (BChE) inhibitor. Octahydroaminoacridine succinate can be used for Alzheimer's disease (AD) research[1].

References

[1] Jiangbin Han, et al. Quantitation of the tacrine analogue octahydroaminoacridine in human plasma by liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 2009 Sep 8;50(2):171-4. DOI:10.1016/j.jpba.2009.03.022

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