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2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL

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2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL Basic information

Product Name:
2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL
Synonyms:
  • 2-(DI-TERT-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL
  • 2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL
  • 2-Di-t-butylphosphino-2'-methylbiphenyl,99%
  • PHOSPHINE, BIS(1,1-DIMETHYLETHYL)(2''-METHYL[1,1''-BIPHENYL]-2-YL)-
  • tBuMePhos
  • 2-(Di-tert-butylphosphino)-2'-methyl- biphenyl, 98+%
  • 2-(Di-tert-butylphosphino)-2'-methylbiphenyl ,99%
  • Di-tert-butyl(2'-Methylbiphenyl-2-yl)phosphine
CAS:
255837-19-5
MF:
C21H29P
MW:
312.43
EINECS:
607-748-2
Product Categories:
  • Achiral Phosphine
  • Aryl Phosphine
Mol File:
255837-19-5.mol
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2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL Chemical Properties

Melting point:
91-93 °C
Boiling point:
408.0±24.0 °C(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
form 
Crystalline Powder
color 
White
Sensitive 
Air Sensitive
InChI
InChI=1S/C21H29P/c1-16-12-8-9-13-17(16)18-14-10-11-15-19(18)22(20(2,3)4)21(5,6)7/h8-15H,1-7H3
InChIKey
UJONYAVMBYXBJQ-UHFFFAOYSA-N
SMILES
P(C(C)(C)C)(C(C)(C)C)C1=CC=CC=C1C1=CC=CC=C1C
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26
WGK Germany 
3
TSCA 
No
HS Code 
29319090

MSDS

  • Language:English Provider:ACROS
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2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL Usage And Synthesis

Description

2-(Di-t-butylphosphino)-2'-methylbiphenyl is a phosphine that has two functional groups, amide and aromatic hydrocarbon. The geometric isomers of this molecule are cis and trans. It can be used to diagnose reactions in a reaction vessel with mammalian cells. It also reacts with pyrazoles, triazoles and other molecules to form isomers at the 2 position of the biphenyl ring.

Chemical Properties

White crystalline powder

Uses

suzuki reaction

Uses

A ligand for the palladium-catalyzed monoarylation of malonate esters, 1,3-diketones and isolated nitroalkanes.

Application

2-(Di-t-butylphosphino)-2'-methylbiphenyl has been shown to have cancer chemotherapeutic potential, as it inhibits the growth of cancer cells by binding to DNA and inhibiting its transcription. This compound also induces apoptosis in some cancer cells.

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