HO-PEG10-CH2COOH
HO-PEG10-CH2COOH Basic information
- Product Name:
- HO-PEG10-CH2COOH
- Synonyms:
-
- HO-PEG10-CH2COOH
- 32-Hydroxy-3,6,9,12,15,18,21,24,27,30-decaoxadotriacontan-1-oic acid
- CAS:
- 2250056-53-0
- MF:
- C22H44O13
- MW:
- 516.58
- Mol File:
- 2250056-53-0.mol
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HO-PEG10-CH2COOH Chemical Properties
- Boiling point:
- 604.7±50.0 °C(Predicted)
- Density
- 1.154±0.06 g/cm3(Predicted)
- pka
- 3.39±0.10(Predicted)
- form
- Oil
- color
- Colorless to light yellow
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HO-PEG10-CH2COOH Usage And Synthesis
Biological Activity
HO-PEG10-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
HO-PEG10-CH2COOHSupplier
TargetMol Chemicals Inc.
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Shanghai Haohong Pharmaceutical Co., Ltd.
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Beijing Jin Ming Biotechnology Co., Ltd.
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TargetMol Chemicals Inc.
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Shanghai Yifei Biotechnology Co. , Ltd.
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