N-(Azido-PEG4)-Biocytin Chemical Properties

solubility 

Soluble in Water, DMSO, DMF

form 

Solid

color 

White to off-white

N-(Azido-PEG4)-Biocytin Usage And Synthesis

Description

N-(Azido-PEG4)-biocytin is a biotin PEG linker containing a carboxylic group and an azide group. Reaction of carboxylic with primary amino (-NH2) forms stable, irreversible amide bonds. The azide group can react with alkyne moiety in Cu(I)-catalyzed Click Chemistry reaction or DBCO moiety in copper-free Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media of the molecules conjugated to the biotin compound.