Basic information Safety Supplier Related

Eplerenone 7-Carboxylic Acid Impurity

Basic information Safety Supplier Related

Eplerenone 7-Carboxylic Acid Impurity Basic information

Product Name:
Eplerenone 7-Carboxylic Acid Impurity
Synonyms:
  • Eplerenone Impurity D
  • FLTCRAGDAAVKPG-ALROZPJCSA-N
  • (2'R,4aS,4bR,5aR,6aS,10R)-4a,6a-dimethyl-2,5'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylic acid
  • Eplerenone EP Impurity D
  • Eplerenone 7-Carboxylic Acid Impurity
  • Eplerenone Impurity 15(Eplerenone EP Impurity D)
  • Eplerenone EP Imp D
  • Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17-hydroxy-3-oxo-, γ-lactone, (7α,11α,17α)-
CAS:
209253-82-7
MF:
C23H28O6
MW:
400.47
Mol File:
209253-82-7.mol
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Eplerenone 7-Carboxylic Acid Impurity Chemical Properties

Boiling point:
653.0±55.0 °C(Predicted)
Density 
1.37±0.1 g/cm3(Predicted)
solubility 
Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly), Ethyl Acetate (Slightly)
pka
4.48±0.60(Predicted)
form 
Solid
color 
Off-White to Light Yellow
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Eplerenone 7-Carboxylic Acid Impurity Usage And Synthesis

Uses

Eplerenone 7-Carboxylic Acid is an impurity of Eplerenone (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.

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