BDP FL-PEG5-acid Chemical Properties

solubility 

Soluble in DMSO, DMF, DCM, low solubility in water

BDP FL-PEG5-acid Usage And Synthesis

Description

BDP FL-PEG5-acid is a BDP FL acid linker containing a hydrophilic PEG spacer arm.

BDP FL is a green-fluorescent dye and the hydrophilic PEG spacer arm increases water solubility as well as membrane permability. BDP FL dye has several characteristics that make it potentially superior in some applications, including high extinction coefficient, high fluorescence quantum yield, narrow emission bandwidth, red shift in fluorescence emission at high dye concentrations, relatively long excited-state lifetime, etc.

Uses

BDP FL-PEG5-acid is a BDP FL acid linker containing a hydrophilic PEG spacer arm. BDP FL-PEG5-acid can be used in the synthesis of PROTACs. BDP FL is a green-fluorescent dye, and the hydrophilic PEG spacer arm increases water solubility and membrane permability.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005