9,11-DIOXO-15S-HYDROXY-PROST-13E-EN-1-OIC ACID Chemical Properties

Boiling point:

551.8±50.0 °C(Predicted)

Density 

1.127±0.06 g/cm3(Predicted)

solubility 

DMF: >100 mg/ml (from PGD2); DMSO: >50 mg/ml (from PGD2); Ethanol: >75 mg/ml (from PGD2); PBS pH 7.2: >2.7 mg/ml (from 15-deoxy-d12,

pka

4.77±0.10(Predicted)

9,11-DIOXO-15S-HYDROXY-PROST-13E-EN-1-OIC ACID Usage And Synthesis

Description

Prostaglandin K₁ (PGK₁) is a 9,11-diketo analog of PGE₁ or PGD₁ . It is a PGE₂ receptor subtype EP₁ agonist that has 387-fold reduced potency compared to PGE₂ .¹

Definition

ChEBI: PGK1 is a prostanoid.

References

1. Ungrin, M.D., Carrière, M.C., Denis, D., et al. Key structural features of prostaglandin E₂ and prostanoid analogs involved in binding and activation of the human EP₁ prostanoid receptor Mol. Pharmacol. 59(6),1446-1456(2001).

9,11-DIOXO-15S-HYDROXY-PROST-13E-EN-1-OIC ACID(69413-73-6)Related Product Information

• 11-DEOXY PROSTAGLANDIN E1
• 3,5-HEPTANEDIONE
• 9,11-DIOXO-15S-HYDROXY-PROST-13E-EN-1-OIC ACID
• 1,3-Cyclopentanedione