XDXWLKQMMKQXPV-PHYJMDTMSA-N Chemical Properties

solubility 

Chloroform (Slightly), DMSO (Sparingly)

form 

Solid

color 

Light Orange to Orange

XDXWLKQMMKQXPV-PHYJMDTMSA-N Usage And Synthesis

Uses

An agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia

Biological Activity

(E/Z)-Eltrombopag 13C ((E/Z)-SB-497115 13C) is a mixture complex of E-Eltrombopag and Z-Eltrombopag, with 13C labeled. Z-Eltrombopag is a thrombopoietin (TPO) receptor agonist developed for certain conditions that lead to thrombocytopenia[1].

References

[1]. Erickson-Miller CL, et al. Preclinical activity of eltrombopag (SB-497115), an oral, nonpeptide thrombopoietin receptor agonist. Stem Cells. 2009 Feb;27(2):424-30.

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