XDXWLKQMMKQXPV-PHYJMDTMSA-N

Product Name: XDXWLKQMMKQXPV-PHYJMDTMSA-N
CAS No.: 1217230-31-3
Chemical Name: XDXWLKQMMKQXPV-PHYJMDTMSA-N
Synonyms: [13C4]-Eltrombopag;(E/Z)-Eltrombopag-13C4;Eltrombopag Impurity 47;XDXWLKQMMKQXPV-PHYJMDTMSA-N;[13C4]-Eltrombopag (Novartis number ETB115)
CBNumber: CB93406354
Molecular Formula: C25H22N4O4
Formula Weight: 446.50258
MOL File: 1217230-31-3.mol

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XDXWLKQMMKQXPV-PHYJMDTMSA-N Property

solubility: Chloroform (Slightly), DMSO (Sparingly)
form: Solid
color: Light Orange to Orange

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: E508002
Product name: Eltrombopag-13C4
Packaging: 1mg
Price: $145
Updated: 2021/12/16

TRC

Product number: E508002
Product name: Eltrombopag-13C4
Packaging: 2.5mg
Price: $245
Updated: 2021/12/16

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XDXWLKQMMKQXPV-PHYJMDTMSA-N Chemical Properties,Usage,Production

Uses

An agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia

Biological Activity

(E/Z)-Eltrombopag 13C ((E/Z)-SB-497115 13C) is a mixture complex of E-Eltrombopag and Z-Eltrombopag, with 13C labeled. Z-Eltrombopag is a thrombopoietin (TPO) receptor agonist developed for certain conditions that lead to thrombocytopenia[1].

References

[1]. Erickson-Miller CL, et al. Preclinical activity of eltrombopag (SB-497115), an oral, nonpeptide thrombopoietin receptor agonist. Stem Cells. 2009 Feb;27(2):424-30.

XDXWLKQMMKQXPV-PHYJMDTMSA-N Preparation Products And Raw materials

Raw materials

Preparation Products

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1217230-31-3, XDXWLKQMMKQXPV-PHYJMDTMSA-NRelated Search:

3'-aMino-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid hydrochloride 5-Chloro-2-hydroxy-3-nitro-(1,1-biphenyl)-3-carboxylic acid

XDXWLKQMMKQXPV-PHYJMDTMSA-N

[13C4]-Eltrombopag

Eltrombopag Impurity 47

[13C4]-Eltrombopag (Novartis number ETB115)

(E/Z)-Eltrombopag-13C4

1217230-31-3