MALONYL COENZYME A TETRALITHIUM SALT Chemical Properties

storage temp. 

-20°C

solubility 

H₂O: 50 mg/mL, clear, colorless

form 

solid

Water Solubility 

H2O: 50mg/mL, clear, colorless

Safety Information

WGK Germany 

3

F 

10-21

MSDS

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MALONYL COENZYME A TETRALITHIUM SALT Usage And Synthesis

Uses

Malonyl CoA (Malonyl coenzyme A) tetralithium is a substrate for fatty acid biosynthesis and an inhibitor of fatty acid oxidation. Malonyl CoA tetralithium is also a reversible inhibitor of mitochondrial carnitine palmitoyltransferase (CPT) 1[1][2].

Biochem/physiol Actions

Malonyl Coenzyme A is a Coenzyme A derivative that is utilized in fatty acid and polyketide synthesis and in the transport of α-ketoglutarate across the mitochondrial membrane. Malonyl CoA is formed by the Acetyl CoA Carboxylase-mediated carboxylation of acetyl CoA.

References

[1] B E Corkey, et at. A role for malonyl-CoA in glucose-stimulated insulin secretion from clonal pancreatic beta-cells. J Biol Chem. 1989 Dec 25;264(36):21608-12. PMID:2689441

MALONYL COENZYME A TETRALITHIUM SALT(116928-84-8)Related Product Information

• Coenzyme A