Basic information Safety Supplier Related

2-(METHYLTHIO)-ADENOSINE 5'-TRIHYDROGEN DIPHOSPHATE TRISODIUM

Basic information Safety Supplier Related

2-(METHYLTHIO)-ADENOSINE 5'-TRIHYDROGEN DIPHOSPHATE TRISODIUM Basic information

Product Name:
2-(METHYLTHIO)-ADENOSINE 5'-TRIHYDROGEN DIPHOSPHATE TRISODIUM
Synonyms:
  • 2-methylthioadenosine-5’-o-diphosphate(2-mes-atp),sodiumsalt
  • methylthio-adp
  • 2-(METHYLTHIO)-ADENOSINE 5'-TRIHYDROGEN DIPHOSPHATE TRISODIUM
  • 2-(METHYLTHIO)ADENOSINE-5'-(TRIHYDROGEN DIPHOSPHATE) TRISODIUM SALT
  • 2-METHYLTHIOADENOSINE DIPHOSPHATE TRISODIUM
  • 2-METHYLTHIO-ADP TRISODIUM
  • 2-METHYLTHIO-ADP TRISODIUM SALT
  • 2-(Methylthio)adenosine-5'-(trihydrogenediphosphate)trisodiumsalt
CAS:
34983-48-7
MF:
C11H17N5O10P2S
MW:
473.29
Product Categories:
  • Purinergics P2 receptor
Mol File:
34983-48-7.mol
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2-(METHYLTHIO)-ADENOSINE 5'-TRIHYDROGEN DIPHOSPHATE TRISODIUM Chemical Properties

Boiling point:
936.1±75.0 °C(Predicted)
Density 
2.35±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: 35 mg/mL
form 
solid
pka
1.39±0.10(Predicted)
color 
white
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3

MSDS

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2-(METHYLTHIO)-ADENOSINE 5'-TRIHYDROGEN DIPHOSPHATE TRISODIUM Usage And Synthesis

Uses

2-Methylthio-ADP trisodium salt is a P2Y1, P2Y12 and P2Y13 agonist. It is used in biological study of activation of P2Y1 P2Y12 and P2Y13 protein promoted purinergic ATP signal transduction mediated calcium flux in podocyte isolated from rat glomerulus.

Biological Activity

Potent purinergic agonist displaying selectivity for P2Y 1 , P2Y 12 and P2Y 13 receptors (pEC 50 = 8.29 and 9.05 for P2Y 1 and P2Y 12 , EC 50 = 19 nM for P2Y 13 ). Induces aggregation of, and inhibits cAMP accumulation in, platelets in vitro .

2-(METHYLTHIO)-ADENOSINE 5'-TRIHYDROGEN DIPHOSPHATE TRISODIUMSupplier

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