N-DESMETHYLDILTIAZEM, HYDROCHLORIDE Chemical Properties

Melting point:

156-158°C

storage temp. 

Hygroscopic, -20°C Freezer, Under Inert Atmosphere

solubility 

Chloroform (Slightly), Methanol (Slightly), Water (Slightly)

form 

Solid

color 

White to Off-White

Stability:

Hygroscopic

N-DESMETHYLDILTIAZEM, HYDROCHLORIDE Usage And Synthesis

Chemical Properties

White Solid

Uses

A metabolite of diltiazem, an antianginal, antihypertensive pharmaceutical. Diltiazem regulates Calcium release from intracellular stores in neutrophils

Uses

A metabolite of Diltiazem (D460620), an antianginal, antihypertensive pharmaceutical. Diltiazem regulates Calcium release from intracellular stores in neutrophils.

Uses

N-Desmethyl Diltiazem Hydrochloride (Dilitiazem EP Impurity D) is a metabolite of Diltiazem (D460620), an antianginal and an antihypertensive pharmaceutical. Diltiazem regulates calcium release from intracellular stores in neutrophils.

N-DESMETHYLDILTIAZEM, HYDROCHLORIDE(130606-60-9)Related Product Information

• O-Desmethyl Diltiazem Hydrochloride
• 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, (2S-trans)-
• (2R-cis)-3-acetoxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride
• N,N-Didesmethyl Diltiazem Hydrochloride
• Diltiazem N-Oxide
• Diltiazem impurity
• diltiazem hydrochloride
• Deacetyl-O-demethyl Diltiazem Hydrochloride
• O-Desacetyl-N-desmethyl Diltiazem
• Diltiazem Impurity 3
• (2S,3S)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 1-oxide
• DESACETYL DILTIAZEM HCL
• (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one
• Diltiazem EP Impurity B
• Diltiazem EP Impurity C
• Diltiazem hydrochloride
• DESACETYL DILTIAZEM HYDROCHLORIDE (50 MG)
• DESMETHYL DILTIAZEM HCL