OCTYL THIOMALTOSIDE Chemical Properties

Boiling point:

706.4±60.0 °C(Predicted)

Density 

1.38±0.1 g/cm3(Predicted)

pka

12.89±0.70(Predicted)

PH

5-8 (1% (w/v) in H2O)

λmax

λ: 260 nm Amax: ≤0.20
λ: 280 nm Amax: ≤0.15

Safety Information

WGK Germany 

3

OCTYL THIOMALTOSIDE Usage And Synthesis

Uses

Octyl thiomaltoside (OTM) is a nonionic detergent commonly used in the purification and crystallization of membrane proteins. It belongs to the family of maltoside detergents and has a hydrophilic head group and a lipophilic tail group, enabling it to interact with water-soluble and membrane-bound proteins. OTMs are known for their ability to solubilize integral membrane proteins without disrupting their structure or function, making them an invaluable tool in biochemical and biophysical research. In addition to protein research, OTMs are used in a variety of other applications, including drug delivery systems, nanotechnology, and diagnostic analysis.

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