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N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE

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N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE Basic information

Product Name:
N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE
Synonyms:
  • N-HEPTYL-BETA-D-THIOGLC
  • N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE
  • N-HEPTYL BETA-D-THIOGLUCOSIDE
  • N-HEPTYL-BETA-D-THIOGLYCOSIDE
  • N-HEPTYL-1-THIO-BETA-D-GLUCOPYRANOSIDE
  • HEPTYL-THIOGLUCOSIDE
  • HEPTYL B-D-THIOGLUCOPYRANOSIDE
  • HEPTYL-BETA-D-1-THIOGLUCOPYRANOSIDE
CAS:
85618-20-8
MF:
C13H26O5S
MW:
294.41
EINECS:
1533716-785-6
Product Categories:
  • 13C & 2H Sugars
  • Carbohydrates & Derivatives
  • Detergents
  • Glycon Biochem
Mol File:
85618-20-8.mol
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N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE Chemical Properties

Melting point:
96.1-98.3°C
Boiling point:
479.9±45.0 °C(Predicted)
Density 
1.23±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
methanol: 0.1 g/mL, clear, yellow
pka
13.02±0.70(Predicted)
form 
Solid
color 
White Waxy
BRN 
6057483
CAS DataBase Reference
85618-20-8(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
3-10
HS Code 
29329990

MSDS

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N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE Usage And Synthesis

Chemical Properties

White Paste

Uses

n-Heptyl β-D-thioglucopyranoside is useful non-ionic detergent for solubilization and reconstitution of membrane proteins of Escherichia coli.

Purification Methods

The tetraacetyl derivative is purified by silica gel column chromatography and eluted with a *C6H6/Me2CO gradient (up to 5% of Me2CO) and recrystallises from n-hexane as colourless needles m 72-74o (Erbing & Lindberg Acta Chem Scand B30 611 1976 gave m 69-70o). Hydrolysis with an equivalent of base in methanol gives the desired glucoside. This is a non-ionic detergent for reconstituting membrane proteins and has a critical micelle concentration of 30 mM. [Shimamoto et al. J Biochem (Tokyo) 97 1807 1985; Saito & Tsuchiya Chem Pharm Bull Jpn 33 503 1985].

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