Chitosan Oligosaccharide Usage And Synthesis

Description

Chitosan oligosaccharide (COS) is an oligomer of β-(1?4)-linked d-glucosamine. COS can be prepared from the deacetylation and hydrolysis of chitin, commonly found in the exoskeletons of arthropods and insects and the cell walls of fungi. COS is water soluble, non-cytotoxic, readily absorbed through the intestine, and mainly excreted in the urine. Of particular importance, COS and its derivatives have been demonstrated to possess several biological activities, including anti-inflammation, immunostimulation, anti-tumor, anti-obesity, anti-hypertension, anti-Alzheimer's disease, tissue regeneration promotion, drug and DNA delivery enhancement, anti-microbial, anti-oxidation, and calcium-absorption enhancement. The mechanisms of actions of COS have been found to involve the modulation of several vital pathways, including the suppression of nuclear factor kappa B (NF-κB) and mitogen-activated protein kinases (MAPK) and the activation of AMP-activated protein kinase (AMPK)[1].

References

[1] Chatchai Muanprasat, Varanuj Chatsudthipong. “Chitosan oligosaccharide: Biological activities and potential therapeutic applications.” Pharmacology & Therapeutics 170 (2017): Pages 80-97.

Chitosan Oligosaccharide()Related Product Information

• Pectin
• beta-Sitosterol
• Magnesium stearate
• LACTITOL
• Polydextrose
• STACHYOSE TETRAHYDRATE
• DL-Arabinose
• 4-Aminobutyric acid
• Sodium alginate
• Phosphatidylserine
• Chitin
• Carboxymethyl chitosan
• Chitosan Hydrochloride
• Quaternary chitosan
• Guar gum
• CHITOSAN LACTATE
• Chitosan
• Ganoderma spore powder