5-Amino-6-methyl-1,3-dihydro-2H-benzimidazol-2-one Chemical Properties

Melting point:

>256°C (dec.)

Boiling point:

215.0±29.0 °C(Predicted)

Density 

1.298±0.06 g/cm3(Predicted)

vapor pressure 

0.023Pa at 20℃

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

11.81±0.30(Predicted)

form 

Solid

color 

Pale Beige to Light Brown

Water Solubility 

1.72g/L at 19.5℃

LogP

0.2 at 20℃

CAS DataBase Reference

67014-36-2(CAS DataBase Reference)

Safety Information

HazardClass 

IRRITANT

HS Code 

2933998090

5-Amino-6-methyl-1,3-dihydro-2H-benzimidazol-2-one Usage And Synthesis

Uses

5-Amino-6-methylbenzimidazolone is used in preparing colorant for color filters.

Synthesis

The 500 ml four-necked bottle was fitted with stirring, condenser, thermometer and heating jacket, then 250 g of 85% ethanol-water solution was added to it, stirring was turned on, and 16.8 g (0.3 mol) of iron powder and 5.0 g of hydrochloric acid with a concentration of 36% were added sequentially under stirring conditions, and then after the addition, the stopper of the bottle was capped, the reflux condenser was turned on to cool the water, and the heating system was turned on to heat the system to boiling under stirring conditions for 30 minutes. The temperature of the system was heated to boiling under stirring conditions, and the activation was held under boiling conditions for 30 min, and then 15 g (0.078 mol) of 5-nitro-6-methylbenzimidazolone was uniformly added to the system within 4.0 h. During the period, the material was added every 5 min, and the temperature was always maintained at reflux, and the reaction was continued to hold the reaction under reflux conditions for 4.0 h after the addition. After holding the reaction for a period of 4.0 h, the reaction solution was neutralized with sodium carbonate to a pH = 6.5-6.0%. PH = 6.5-7.0, continue stirring for 10 minutes, then stop stirring, holding and settling for 20 minutes, filtered with a preheated to nearly 100 ?? Brinell funnel, the iron slurry with 200 ml of concentration of 85% ethanol reflux slurry for 30 minutes, then stop stirring, holding and settling for 20 minutes, filtration, the combined mother liquor and the wash solution, the natural stationary cooling, when cooled down to room temperature, filtration, and the resulting product in the The product was dried at 50??C under infrared lamp to obtain 11.4g of product with 99.1% purity, white flaky crystals and 89.2% yield.

5-Amino-6-methyl-1,3-dihydro-2H-benzimidazol-2-one(67014-36-2)Related Product Information

• benzimidazol-2-one
• 5-amino-6-phenyl-1,3-dihydro-2H-benzimidazol-2-one
• 5-AMINO-1,3,6-TRIMETHYL-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE
• 5-AMINO-1,3-DIETHYL-6-METHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE
• 5-amino-6-thien-2-yl-1,3-dihydro-2H-benzimidazol-2-one
• 5-Amino-6-methyl-1,3-dihydro-2H-benzimidazol-2-one