2-Methylglutaric Acid Chemical Properties

Melting point:

80-82 °C(lit.)

Boiling point:

214-215 °C22 mm Hg(lit.)

Density 

1.246

vapor pressure 

0.001Pa at 20℃

Flash point:

149℃

storage temp. 

Store below +30°C.

solubility 

DMF: 20 mg/ml; DMSO: 16 mg/ml; Ethanol: Slightly soluble; PBS (pH 7.2): 10 mg/ml

form 

powder to crystal

pka

4.57±0.10(Predicted)

color 

White to Light yellow

Water Solubility 

Soluble in water.

InChI

InChI=1S/C6H10O4/c1-4(6(9)10)2-3-5(7)8/h4H,2-3H2,1H3,(H,7,8)(H,9,10)

InChIKey

AQYCMVICBNBXNA-UHFFFAOYSA-N

SMILES

C(O)(=O)C(C)CCC(O)=O

LogP

-1.3 at 20℃

EPA Substance Registry System

2-Methylglutaric acid (617-62-9)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

2917198090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Methylglutaric Acid Usage And Synthesis

Description

(2)-Methylglutaric acid is a metabolite found in or produced by Saccharomyces cerevisiae. It is used in of sparsely pillared organic-inorganic hybrid compound.

Uses

2-Methylglutaric acid is used as primary and secondary intermediates in pharmaceutical and chemical research.

Definition

ChEBI: 2-methylglutaric acid is an alpha,omega-dicarboxylic acid that is glutaric acid substituted at position 2 by a methyl group. It has a role as a mammalian metabolite. It is an alpha,omega-dicarboxylic acid and a dicarboxylic fatty acid. It is functionally related to a glutaric acid. It is a conjugate acid of a 2-methylglutarate(2-).

Flammability and Explosibility

Non flammable

References

1. Effects of Relative Humidity and Particle Phase Water on the Heterogeneous OH Oxidation of 2-Methylglutaric Acid Aqueous Droplets. DOI:10.1021/acs.jpca.6b11606
2. Synthesis of 2‐Methylglutaric Acid by Oxidation of 3‐Methyl‐1,2‐ cyclopentanedione on Anodically Generated Ce(IV). DOI:10.1002/chin.199538117

2-Methylglutaric Acid(617-62-9)Related Product Information

• 2-METHYLGLUTARIC ACID
• 3-Methylglutaric acid dimethyl,3-Methylglutaric acid dimethyl ester
• 2-Methylglutaric acid diethyl ester
• 2-Methylglutaric acid dimethyl ester
• [R,(-)]-2-Methylglutaric acid dimethyl ester
• (R)-2-Amino-2-methylglutaric acid
• 2-Ethyl-4-methylglutaric acid bis[2-(2-ethoxyethoxy)ethyl] ester
• (2R,3R)-2-[[(1R,4R)-Bornan-2-ylidene]amino]-3-methylglutaric acid 1-tert-butyl 5-methyl ester
• 2-Ethyl-4-methylglutaric acid bis[2-(2-butoxyethoxy)ethyl] ester
• 3-Methylglutaric acid bis(2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl) ester
• 2-Ethyl-4-methylglutaric acid dipropyl ester
• 3-Ethyl-4-methylglutaric acid bis[2-(2-methoxyethoxy)ethyl] ester
• 3-Methylglutaric acid bis(2-methoxyethyl) ester
• 3-Methylglutaric acid bis(2-ethoxyethyl) ester
• (2R,3R)-2-[[(1R,4R)-Bornan-2-ylidene]amino]-3-methylglutaric acid 1-ethyl 5-methyl ester
• 3-Methylglutaric acid bis(2-ethoxypropyl) ester
• 2-Ethyl-4-methylglutaric acid bis[2-(2-methoxyethoxy)ethyl] ester
• 3-Methylglutaric acid bis(3-methoxybutyl) ester