PP2A Chemical Properties

storage temp. 

-70°C

form 

buffered aqueous glycerol solution

Safety Information

WGK Germany 

1

PP2A Usage And Synthesis

General Description

Protein phosphatase 2A-α (PP2A-α) is also known as protein phosphatase 2A activator. PP2A is one of the four major serine/threonine phosphatases and is a human tumor suppressor that inhibits cellular transformation. PP2A α gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase-2A. Protein phosphatase 2A holoenzyme is a heterotrimeric protein composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. PTP2A α can alter the substrate specificity of PP2A leading to enhanced phosphotyrosine phosphatase activity and decreased phosphoserine phosphatase activity. The gene encoding this protein is localized on human chromosome 5q31.1.

PP2A()Related Product Information

• PP2