Phenylarsine oxide Chemical Properties

Melting point:

145-148 °C

storage temp. 

Poison room

solubility 

DMSO: 50 mg/mL

form 

powder

color 

white to yellow

biological source

synthetic (organic)

Water Solubility 

Soluble in dimethyl sulfoxide, chloroform, benzene, ether, ethanol, 50:50 dimethyl sulfoxide:1 M hydrochloric acid (3.0 mg/ml) and toluene. Insoluble in water.

Merck 

14,6949

BRN 

2935227

Stability:

Stable.

InChI

InChI=1S/C6H5AsO/c8-7-6-4-2-1-3-5-6/h1-5H

InChIKey

BQVCCPGCDUSGOE-UHFFFAOYSA-N

SMILES

[As](=O)C1=CC=CC=C1

CAS DataBase Reference

637-03-6(CAS DataBase Reference)

EPA Substance Registry System

Oxophenylarsine (637-03-6)

Safety Information

Hazard Codes 

T,N

Risk Statements 

23/25-50/53

Safety Statements 

20/21-28-45-60-61

RIDADR 

UN 3465 6.1/PG 3

WGK Germany 

3

RTECS 

CH8100000

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29310099

Toxicity

LD50 ipr-mus: 1930 mg/kg JPETAB 74,210,42

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Phenylarsine oxide Usage And Synthesis

Chemical Properties

WHITE TO ALMOST WHITE CRYSTALS OR CRYST. POWDER

Uses

Pesticide.

Uses

Phenylarsine oxide is used as a poultry coccidiostat in veterinary medicine. It is also used in a membrane-permeable protein tyrosine phosphatase inhibitor.

Definition

ChEBI: An arsine oxide derived from phenylarsine.

General Description

Phenylarsine oxide (PhAsO⁴) is a bifunctional SH group chemical. It is hydrophobic in nature.

reaction suitability

reagent type: catalyst
core: arsenic

Biochem/physiol Actions

Phenylarsine oxide?(PAO) can reduce the motility and sustainability of Setaria cervi. It has the ability to stimulate cyclosporin A-sensitive transition in the presence of EGTA (ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid). It acts as a stimulator of mitochondrial ion fluxes.

Safety Profile

Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits toxic fumes of As. See also ARSENIC COMPOUNDS

Phenylarsine oxide(637-03-6)Related Product Information

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