Proteinase, Bacillus subtilis, sutilain Chemical Properties

EPA Substance Registry System

Proteinase, Bacillus subtilis, sutilains (12211-28-8)

Proteinase, Bacillus subtilis, sutilain Usage And Synthesis

Uses

Enzyme (proteolytic).

brand name

Travase (Abbott).

General Description

Sutilains (Travase) is a proteolyticenzyme obtained from cultures of Bacillus subtilis and usedto dissolve necrotic tissue occurring in second- and thirddegreeburns as well as bed sores and ulcerated wounds.
Many substances are contraindicated during the topicaluse of sutilains. These include detergents and anti-infectivesthat denature the enzyme preparation. The antibioticspenicillin, streptomycin, and neomycin do not inactivatesutilains. Mafenide acetate is also compatible with theenzyme.

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