Basic information Safety Supplier Related

1-methyl-4-nitrosopiperazine

Basic information Safety Supplier Related

1-methyl-4-nitrosopiperazine Basic information

Product Name:
1-methyl-4-nitrosopiperazine
Synonyms:
  • n-methyl-npz
  • 4-Methyl-1-nitrosopiperazine
  • 1-methyl-4-nitrosopiperazine
  • N-nitroso-N'-methylpiperazine
  • NITROSO-N-METHYLPIPERAZINE
  • 1-NITROSO-4-METHYLPIPERAZINE
  • NITROSOMETHYLPIPERAZINE
  • N-METHYLNITROSOPIPERAZINE
CAS:
16339-07-4
MF:
C5H11N3O
MW:
129.16
EINECS:
2404093
Mol File:
16339-07-4.mol
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1-methyl-4-nitrosopiperazine Chemical Properties

Boiling point:
239.23°C (rough estimate)
Density 
1.1508 (rough estimate)
refractive index 
1.5070 (estimate)
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
Oil
pka
6.50±0.42(Predicted)
color 
Clear Light Yellow
Stability:
Light Sensitive
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Safety Information

Toxicity
LD50 orl-rat: 100 mg/kg ZEKBAI 69,103,67
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1-methyl-4-nitrosopiperazine Usage And Synthesis

Uses

N-Methyl-N’-nitrosopiperazine was used as a reagent in the organic synthesis of several compounds including that of (4-methoxyphenoxy)acetic and (3,4,5-trimethoxyphenoxy)acetic acid amides and hydrazides which display antimicrobial and anthelmintic properties and may act as potential neurotropic and cardiovascular agents. N-Methyl-N’-nitrosopiperazine also diplayed strong nasal carcinogenity and genotoxicity toward nasal cells.

Safety Profile

Poison by ingestion. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. Many N-nitroso compounds are carcinogens. When heated to decomposition it emits toxic fumes of NOx. See also NNITROSO COMPOUNDS.

1-methyl-4-nitrosopiperazine Preparation Products And Raw materials

Raw materials

1-methyl-4-nitrosopiperazineSupplier

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