1-methyl-4-nitrosopiperazine Chemical Properties

Boiling point:

239.23°C (rough estimate)

Density 

1.1508 (rough estimate)

refractive index 

1.5070 (estimate)

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

form 

Oil

pka

6.50±0.42(Predicted)

color 

Clear Light Yellow

Stability:

Light Sensitive

Safety Information

Toxicity

LD50 orl-rat: 100 mg/kg ZEKBAI 69,103,67

1-methyl-4-nitrosopiperazine Usage And Synthesis

Uses

N-Methyl-N’-nitrosopiperazine was used as a reagent in the organic synthesis of several compounds including that of (4-methoxyphenoxy)acetic and (3,4,5-trimethoxyphenoxy)acetic acid amides and hydrazides which display antimicrobial and anthelmintic properties and may act as potential neurotropic and cardiovascular agents. N-Methyl-N’-nitrosopiperazine also diplayed strong nasal carcinogenity and genotoxicity toward nasal cells.

Safety Profile

Poison by ingestion. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. Many N-nitroso compounds are carcinogens. When heated to decomposition it emits toxic fumes of NOx. See also NNITROSO COMPOUNDS.

1-methyl-4-nitrosopiperazine(16339-07-4)Related Product Information

• 1-methyl-4-nitrosopiperazine
• 1-Piperazinecarboximidamide,4-nitroso-(9CI)
• AKOS 94260
• 1-ACETYL-4-NITROSOPIPERAZINE
• 1-BENZOYL-4-NITROSOPIPERAZINE
• 1-BENZYL-4-NITROSOPIPERAZINE
• 4-Benzoyl-3,5-dimethyl N-nitrosopiperazine
• 1-(2,2-DIMETHYLPROPANOYL)-4-NITROSOPIPERAZINE
• N-ISOPROPYL-4-NITROSOPIPERAZINE-1-CARBOXAMIDE
• 1-ISOPROPYL-4-NITROSOPIPERAZINE
• Piperazine,1-acetyl-2,6-dimethyl-4-nitroso-(9CI)
• 1-[[4-(4-Nitroso-1-piperazinyl)-3-pyridinyl]sulfonyl]-piperidine