2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride Chemical Properties

storage temp. 

4°C, away from moisture

form 

powder

color 

Light yellow to green yellow

InChIKey

GFCKACFUYUKAPW-UHFFFAOYSA-N

SMILES

O=C1N(C2CCC(NC2=O)=O)C(C3=CC=C(N4CCNCC4)C=C31)=O

Safety Information

WGK Germany 

WGK 3

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Repr. 1B

2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride Usage And Synthesis

Uses

Thalidomide-piperazine hydrochloride has the potential for the research of leprosy and multiple myeloma. Thalidomide-piperazine hydrochloride used as a tool in developmental biology leads to important discoveries in the biochemical pathways of limb development[1].

Biological Activity

Thalidomide-piperazine hydrochloride has the potential for the research of leprosy and multiple myeloma. Thalidomide-piperazine hydrochloride used as a tool in developmental biology leads to important discoveries in the biochemical pathways of limb development[1].

IC 50

Cereblon

storage

Store at -20°C

References

[1]. Kim JH, et al. Thalidomide: the tragedy of birth defects and the effective treatment of disease [published correction appears in Toxicol Sci. 2012 Feb;125(2):613]. Toxicol Sci. 2011;122(1):1-6.

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