Product Identification

Product Name

Methylsulfonyl chloramphenicol

Synonyms

2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
Dextrosulphenidol
D-threo-2,2-Dichloro-N-(b-hydroxy-a-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide
Methylsulfonylchloramphenicol
Thiocymetin

CAS

15318-45-3

Formula

C12H15Cl2NO5S

Molecular Weight

356.23

EINECS

239-355-3

RTECS

AB6680000

RTECS Class

Reproductive Effector; Human Data

Merck

12,9436

Beilstein/Gmelin

2819542

Beilstein Reference

4-13-00-02957

Physical and Chemical Properties

Solubility in water

Slightly soluble

Melting Point

165 - 166

Vapor Pressure

3E-20 (25 C)

Density

1.55 g/cm3

pKa/pKb

11.05 (pKa)

Partition Coefficient

-.38

Heat Of Vaporization

107.0 kJ/mol

Usage

Veterinary antimicrobial agent.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles.

Respirators

Government approved respirator.

Exposure Effects

Avoid contact and inhalation. Target organ(s): Bone marrow.

Fire Fighting Measures

Fire Fighting

Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides, Hydrogen chloride gas.

Hazards Identification

Hazards

Emits toxic fumes under fire conditions.

EC Safety Phrase

22 24/25