Product Identification

Product Name

Methyl mercaptoacetate

Synonyms

Acetic acid, mercapto-, methyl ester
Methyl 2-mercaptoacetate
Methyl 2-sulfanylacetate
Methyl thioglycolate
Thioglycolic acid methyl ester

CAS

2365-48-2

Formula

C3H6O2S

Molecular Weight

106.14

EINECS

219-121-7

RTECS

AI7350000

RTECS Class

Other

Beilstein/Gmelin

506259

Beilstein Reference

4-03-00-00614

EC Class

toxic, irritant, sensitizing

Physical and Chemical Properties

Appearance

Clear, colorless liquid with a stench.

Solubility in water

Soluble

Melting Point

-3

Boiling Point

152

Vapor Pressure

3.6 (25 C)

Density

1.1629 g/cm3 (20 C)

pKa/pKb

8.22 (pKa)

Partition Coefficient

.65

Heat Of Vaporization

38.9 kJ/mol

Usage

Chemical intermediate.

Vapor Density

3.66

Refractive Index

1.4673 (20 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Skin

Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.

Handling

Wash thoroughly after handling. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Ingestion

Harmful if swallowed.

Inhalation

May cause respiratory tract irritation. Vapors may cause dizziness or suffocation.

Skin

Causes skin irritation.

Eyes

Causes eye irritation.

Hazards

Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.

EC Risk Phrase

R 10 20/22 36/37/38

EC Safety Phrase

S 23 26 36/37/39

UN (DOT)

1993

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Poison Class

3

Fire Fighting Measures

Flash Point

35

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Use agent most appropriate to extinguish fire. Do NOT use straight streams of water. In case of fire use water spray, dry chemical or carbon dioxide.

Fire Potential

Flammable Liquid.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.

Stability and Reactivity

Disposal Code

6

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents, strong bases.

Decomposition

Carbon monoxide, oxides of sulfur, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

1993

Hazard Class

3

Packing Group

I; II; III

HS Code

2930 90 70