Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Hazards Identification
Home > 1alpha,25-Dihydroxycholecalciferol > 1alpha,25-Dihydroxycholecalciferol(32222-06-3)

1alpha,25-Dihydroxycholecalciferol(32222-06-3)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Hazards Identification
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Product Identification

Product Name

1alpha,25-Dihydroxycholecalciferol

Synonyms

1,25-Dihydroxycholecalciferol
1,25-Dihydroxyvitamin D3
9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol, (1a,3b,5Z,7E)-
Calcitriol
Rocaltrol
Topitriol

CAS

32222-06-3

Formula

C27H44O3

Molecular Weight

416.64

EINECS

250-963-8

RTECS

FZ4645000

RTECS Class

Drug; Mutagen; Reproductive Effector

Merck

12,1681

Beilstein/Gmelin

2065599

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Physical and Chemical Properties

Appearance

Colorless, crystalline solid.

Solubility in water

Insoluble

Melting Point

95 - 99

pKa/pKb

13.98 (pKa)

Usage

Medication.

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First Aid Measures

Ingestion

Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.

Inhalation

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.

Skin

Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.

Eyes

If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

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Handling and Storage

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

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Exposure Controls/Personal Protection

Personal Protection

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.

Respirators

Use NIOSH/MSHA approved respirator appropriate for exposure of concern.

Exposure Effects

Symptoms are similar to hypercalcemia: anorexia, fatigue, headache, itching, and weakness. Polyneuropathy has been reported after acute intoxication. In humans, aortic stenosis was associated with high doses of vitamin D in pregnancy. However, conflicting results have been observed. In animal studies, toxic effects including fetotoxicity, spontaneous abortion and specific developmental abnormalities were observed.

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Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

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Accidental Release Measures

Small spills/leaks

Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.

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Stability and Reactivity

Stability

No data.

Incompatibilities

Strong oxidizing agents.

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Hazards Identification

Ingestion

Nausea, vomiting, and diarrhea may be seen.

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ContactMore

Chemvon Biotechnology Co., Ltd
Tel
021-50790412
Fax
+86-21-50790419
WebSite
http://www.chemvon.com
ZHENGZHOU TAIFENG PHARMACEUTICAL CO.,LTD
Tel
182-3786-0830
WebSite
https://www.chemicalbook.com/ShowSupplierProductsList1493154/0.htm
Hangzhou Runyan Medical Technology Co., LTD
Tel
13989459766
WebSite
https://www.runyanpharma.com
Jiangxi ravel Biotechnology Co.,Ltd
Fax
400-880-2824
WebSite
https://www.ruiweier.cn/
Shanghai Hope Chem Co., Ltd.,
Tel
+21-18501659228
Fax
sales@hope-chem.com
WebSite
http://www.hope-chem.com