Product Identification

Product Name

4-Hydroxybenzoic acid propyl ester

Synonyms

Aseptoform P
Benzoic acid, 4-hydroxy-, propyl ester
p-Hydroxybenzoic acid propyl este
Preserval P
Propylparaben
Tegosept P

CAS

94-13-3

Formula

C10H12O3

Molecular Weight

180.21

EINECS

202-307-7

RTECS

DH2800000

RTECS Class

Drug; Mutagen

Merck

12,8051

Beilstein/Gmelin

1103245

Beilstein Reference

4-10-00-00374

Physical and Chemical Properties

Appearance

Colorless crystals or white powder or chunky white solid. Odorless or faint aromatic odor.

Solubility in water

Insoluble

Melting Point

95

Boiling Point

292

Vapor Pressure

0.0009 (25 C)

Density

1.28 g/cm3 (20 C)

pKa/pKb

8.23 (pKa)

Partition Coefficient

3.04

Heat Of Vaporization

55.5 kJ/mol

Heat Of Combustion

-5029 kJ/mol

Usage

Pharmaceutic aid (antifungal), preservative in foods.

Refractive Index

1.505 (102.1 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation.

Hazards Identification

Ingestion

May cause irritation of the digestive tract.

Inhalation

Causes respiratory tract irritation.

Skin

Causes skin irritation. Causes severe and intractable contact dermatitis.

Eyes

Causes eye irritation.

EC Risk Phrase

R 36/37/38

EC Safety Phrase

S 26 36

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Poison Class

5

Fire Fighting Measures

Flash Point

180

Autoignition

> 600

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents - strong bases.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, acrid smoke and fumes.

Transport Information

HS Code

2918 29 30