Product Identification

Product Name

Esfenvalerate

Synonyms

(S)-alpha-Cyano-3-phenoxybenzyl (S)-2-(4-chlorophenyl)-3-methylbutyrate
Asana
S-1844
S-5602-alpha

CAS

66230-04-4

Formula

C25H22ClNO3

Molecular Weight

419.93

RTECS

CY1576367

RTECS Class

Agricultural Chemical and Pesticide; Tumorigen

Beilstein/Gmelin

4275674

EC Index Number

650-033-00-5

Physical and Chemical Properties

Appearance

Viscous yellow or brown liquid.

Solubility in water

< 1 mg/L (20 C)

Melting Point

59-60

Boiling Point

539

Vapor Pressure

1E-11 (25 C)

Density

1.163 g/cm3 (23 C)

Partition Coefficient

7.45

Heat Of Vaporization

81.6 kJ/mol

Usage

Control of a wide range of insect pests on cotton, maize, groundnuts, soya beans, sugar cane, sunflowers, sorghum, fruit trees, vegetables, ornamentals, and noncrop land.

First Aid Measures

Ingestion

There is no specific antidote for pyrethrin poisoning. Treatment is symptomatic and supportive and includes monitoring for the development of hypersensitivity reactions with respiratory distress. Provide adequate airway management when needed. Gastric decontamination is usually not required unless the pyrethrin product is combined with a hydrocarbon. Allergic reaction: mild: antihistamines with or without epinephrine. Severe: oxygen, aggressive airway management, antihistamines, epinephrine (adult: 0.3 To 0.5 Ml of a 1:1000 solution subcutaneously; child: 0.01 Ml/kg; may repeat in 20 to 30 min), corticosteroids, ecg monitoring, and iv fluids.

Inhalation

Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.

Skin

Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Vitamin e topical application is highly effective in relieving paresthesias.

Eyes

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Handling and Storage

Storage

Pyrethrins with piperonyl butoxide topical preparations should be stored in well-closed containers at a temperature less than 40C, preferably between 15-30C.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Ingestion

Nausea, vomiting and abdominal pain commonly occur and develop within 10 to 60 minutes following ingestion.

Inhalation

Hypersensitivity reactions characterized by pneumonitis, cough, dyspnea, wheezing, chest pain, and bronchospasm may occur. Rare cases of respiratory failure and cardiopulmonary arrest have been reported.

Skin

Irritant and contact dermatitis may develop. Erythema which mimics sunburn has also been noted after prolonged repeated exposure.

Exposure Controls/Personal Protection

Personal Protection

Employees should be provided with and required to use dust- and splash-proof safety goggles where pyrethroids may contact the eyes. Employees should be provided with and be required to use impervious clothing, gloves, and face shields (eight-inch minimum). Wear appropriate equipment to prevent: repeated or prolonged skin contact. Wear eye protection to prevent: reasonable probability of eye contact.

Respirators

Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive pressure mode. Any supplied-air respirator with a full face piece and operated in pressure-demand or other positive pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive pressure mode.

Poison Class

3

Fire Fighting Measures

Flash Point

280

Fire Fighting

Use carbon dioxide, foam, or dry chemical on fires involving pyrethroids.

Fire Potential

Pyrethrins. Burn with difficulty.

Accidental Release Measures

Small spills/leaks

Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.

Stability and Reactivity

Incompatibilities

Avoid contact with strong oxidizers. Incompatible with lime and ordinary soaps because acids and alkalies speed up processes of hydrolysis.

Stability

Pyrethrins are stable for long periods in water-based aerosols where emulsifiers give neutral water systems.