Product Identification

Product Name

Albendazole

Synonyms

Albamelin
Carbamic acid, (5-(propylthio)-1H-benzimidazol-2-yl)-, methyl ester
Methyl 5-propylthio-2-benzimidazolecarbamate
SKF 62979
Valbazen
Zentel

CAS

54965-21-8

Formula

C12H15N3O2S

Molecular Weight

265.33

EINECS

259-414-7

RTECS

FD1100000

RTECS Class

Drug; Mutagen; Reproductive Effector; Human Data

Merck

12,211

Beilstein/Gmelin

752696

Physical and Chemical Properties

Appearance

Colorless crystals.

Solubility in water

Insoluble

Melting Point

214 - 215

pKa/pKb

8.38 (pKb)

Usage

Used to treat tapeworm and roundworm infections. It may also be useful for treating a type of intestonal protozoan infection in aids patients.

First Aid Measures

Ingestion

Get medical aid immediately. Wash mouth out with water.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool, dry place. Store in a tightly closed container.

Handling

Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.

Hazards Identification

Ingestion

May cause liver damage. May cause headache. May be harmful if swallowed. May cause allergic reaction. May cause alopecia (loss of hair). May cause bone marrow depression. Causes gastrointestinal tract irritation.

Inhalation

Causes respiratory tract irritation. May be harmful if inhaled. May cause burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting.

Skin

Causes skin irritation. May cause irritation with burning pain, itching and redness. May be harmful if absorbed through the skin. Contact with the skin may cause urticaria (hives).

Eyes

Causes eye irritation.

Exposure Controls/Personal Protection

Personal Protection

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability

Stable under normal shipping and handling conditions.

Incompatibilities

Strong oxidizing agents.

Decomposition

Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide.