Product Identification

Product Name

3-Pyridinecarboxylic acid

Synonyms

3-Pyridinecarboxylic acid
Niacin
Vitamin B3

CAS

59-67-6

Formula

C6H5NO2

Molecular Weight

123.11

EINECS

200-441-0

RTECS

QT0525000

RTECS Class

Drug; Human Data

Merck

12,6612

Beilstein/Gmelin

109591

Beilstein Reference

5-22-02-00057

EC Class

irritant

Physical and Chemical Properties

Appearance

Odorless white crystalline powder with a feebly acid taste.

Solubility in water

17 g/L

Melting Point

142

Boiling Point

258

Vapor Pressure

0.00084 (25 C)

Density

1.473 g/cm3 (20 C)

pKa/pKb

2.17 (pKa)

Partition Coefficient

.36

Heat Of Vaporization

Heat Of Combustion

-2731 kJ/mol

Usage

One of the b vitamins.

Vapor Density

4.25

Refractive Index

1.4936

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a cool, dry place. Store in a tightly closed container.

Handling

Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Keep container tightly closed. Use only in a chemical fume hood.

Hazards Identification

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

May cause skin irritation. Prolonged and/or repeated contact may cause irritation and/or dermatitis. The toxicological properties of this material have not been fully investigated.

Eyes

May cause eye irritation.

EC Risk Phrase

R 36

EC Safety Phrase

S 26 36

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A NIOSH/MSHA approved air purifying dust or mist respirator or European Standard EN 149.

Exposure limit(s)

OEL-RUSSIA:STEL 1 mg/m3

Poison Class

4

Fire Fighting Measures

Flash Point

131

Autoignition

> 365

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam. Use agent most appropriate to extinguish fire.

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Transport Information

HS Code

2936 29 90