Product Identification

Product Name

2,4-Dihydroxy-6-methylpyrimidine

Synonyms

2,4-Dihydroxy-6-methylpyrimidine
6-Methyl-1H-pyrimidine-2,4-dione
6-Methyl-2,4(1H,3H)-pyrimidinedione

CAS

626-48-2

Formula

C5H6N2O2

Molecular Weight

126.12

EINECS

210-949-4

RTECS

YR0700000

RTECS Class

Tumorigen; Reproductive Effector

Merck

12,6213

Beilstein/Gmelin

115647

Beilstein Reference

5-24-07-00006

EC Class

toxic for reproduction

Physical and Chemical Properties

Appearance

White, fine crystalline powder.

Solubility in water

Slightly soluble

Melting Point

117

Boiling Point

358

Partition Coefficient

-1.32

Usage

Radiation-protective agent.

Vapor Density

4.3

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

May cause respiratory tract irritation.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea.

EC Risk Phrase

R 62 63

EC Safety Phrase

S 22 36/37

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

The toxicological properties of this material have not been fully investigated. Possible risks of irreversible effects.

Poison Class

1*

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

3

Incompatibilities

Oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Transport Information

HS Code

2933 59 95