Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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(+/-)-Phenylpropanolamine hydrochloride(154-41-6)

Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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Product Identification

Product Name

(+/-)-Phenylpropanolamine hydrochloride

Synonyms

2-Amino-1-phenylpropan-1-ol hydrochloride
a-(1-Aminoethyl)benzenemethanol hydrochloride, (R*,S*)-(+/-)
DL-Norephedrine hydrochloride

CAS

154-41-6

Formula

C9H14ClNO

Molecular Weight

187.67

EINECS

205-826-7

RTECS

DN4200000

RTECS Class

Drug; Reproductive Effector; Human Data

Merck

12,7461

Beilstein/Gmelin

3914299

Beilstein Reference

2-13-00-00371

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Physical and Chemical Properties

Appearance

Odorless white to creamy-white crystalline powder. Bitter taste.

Solubility in water

Freely soluble

Melting Point

172 - 175

Boiling Point

255 (14 torr)

Density

1.25 g/cm3

pKa/pKb

9.44(at 25℃) (pKa)

Heat Of Vaporization

Usage

Used as a decongestant.

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First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

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Handling and Storage

Storage

Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Use with adequate ventilation.

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Hazards Identification

Ingestion

May cause irritation of the digestive tract. May be harmful if swallowed.

Inhalation

May cause respiratory tract irritation.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

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Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

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Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Fire Potential

This material is probably combustible.

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Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.

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Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.