Product Identification

Product Name

7-Hydroxy-3-(4-methoxyphenyl)chromone

Synonyms

4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-methoxyphenyl)-
7-Hydroxy-3-(4-methoxyphenyl)-4-benzopyrone
7-Hydroxy-4'-methoxyisoflavone
Biochanin
Daidzein 4'-methyl ether
Formononetol

CAS

485-72-3

Formula

C16H12O4

Molecular Weight

268.26

EINECS

207-623-9

Merck

12,4271

Beilstein/Gmelin

237979

Beilstein Reference

5-18-04-00089

Physical and Chemical Properties

Appearance

Solid.

Solubility in water

Insoluble

Melting Point

290 - 293

pKa/pKb

7.54 (pKa)

Usage

Treatment and prevention of osteoporosis.

First Aid Measures

Ingestion

Get medical aid. Wash mouth out with water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a cool, dry place. Store in a tightly closed container.

Handling

Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

Hazards Identification

Ingestion

May cause irritation of the digestive tract. May be harmful if swallowed.

Inhalation

Causes respiratory tract irritation. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. May be harmful if inhaled. May cause burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting.

Skin

Causes skin irritation. May be harmful if absorbed through the skin.

Eyes

Causes eye irritation.

Exposure Controls/Personal Protection

Personal Protection

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability

No data.

Incompatibilities

Strong oxidizing agents, acids, acid chlorides, carbon dioxide, acid anhydrides.

Decomposition

Carbon monoxide, carbon dioxide.