Product Identification

Product Name

4-Butyl-1,2-diphenyl-3,5-pyrazolidinedione

Synonyms

Alindor
Antadol
Anuspiramin
Arthrizon
Artrizin
Azolid

CAS

50-33-9

Formula

C19H20N2O2

Molecular Weight

308.38

EINECS

200-029-0

RTECS

UQ8225000

RTECS Class

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Primary Irritant

Merck

12,7431

Beilstein/Gmelin

290080

Beilstein Reference

5-24-05-00400

Physical and Chemical Properties

Appearance

Odorless white or off-white crystalline powder. Tasteless at first, but slightly bitter aftertaste.

Solubility in water

Slightly soluble

Melting Point

105.5

Boiling Point

425

Vapor Pressure

2E-7 (25 C)

Density

1.22 g/cm3

pKa/pKb

4.42 (pKa)

Partition Coefficient

3.47

Heat Of Vaporization

67.9 kJ/mol

Usage

Medication (vet).

Refractive Index

1.5502

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool, dry place. Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation.

Hazards Identification

Inhalation

Causes respiratory tract irritation.

Skin

Causes skin irritation.

Eyes

Causes eye irritation.

Ingestion

Harmful if swallowed. Causes digestive tract irritation. Ingestion may cause fever, blood pressure increase and other unspecified vascular effects.

EC Risk Phrase

R 20/22 36/37/38 40

EC Safety Phrase

S 26 36/37/39

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Damage to kidney tubules or glomeruli may occur.

Fire Fighting Measures

Flash Point

174

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents - strong acids - strong bases.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.