Product Identification

Product Name

Bromopyruvic acid

Synonyms

3-Bromo-2-oxopropanoic acid
3-Bromopyruvate
3-Bromopyruvic acid
beta-Bromopyruvic acid

CAS

1113-59-3

Formula

C3H3BrO3

Molecular Weight

166.92320000000001

EINECS

214-206-5

RTECS

UZ0840000

RTECS Class

Other

Beilstein/Gmelin

1746786

Beilstein Reference

3-03-00-01167

Physical and Chemical Properties

Appearance

Colorless to white solid.

Solubility in water

Very soluble

Melting Point

77 - 79

Boiling Point

249

pKa/pKb

1.84 (pKa)

Partition Coefficient

-.03

Usage

Being studied as a potential treatment for certain types of cancer.

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.

Eyes

Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Handling and Storage

Storage

Keep container closed when not in use. Corrosives area. Storage at 2-8C is recommended.

Handling

Keep container tightly closed. Do not get on skin or in eyes. Do not ingest or inhale. Use with adequate ventilation. Discard contaminated shoes.

Hazards Identification

Ingestion

May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns.

Inhalation

Causes chemical burns to the respiratory tract.

Skin

Causes skin burns.

Eyes

Causes eye burns.

Hazards

Contact with metals may evolve flammable hydrogen gas.

EC Risk Phrase

R 22 34

EC Safety Phrase

S 26 36/37/39 45

UN (DOT)

1759

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: Cool containers with flooding quantities of water until well after fire is out. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Incompatibilities

Strong oxidizing agents.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, bromine fumes, bromine.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

1759

Hazard Class

8

Packing Group

I; II; III