Product Identification

Product Name

2,6-Diamino-3-phenylazopyridine hydrochloride

Synonyms

2,6-Diamino-3-phenylazopyridine hydrochloride
2,6-Pyridinediamine, 3-(phenylazo)-, monohydrochloride
Azodyne
Pyridium
Pyripyridium
Uridinal

CAS

136-40-3

Formula

C11H12ClN5

Molecular Weight

249.7

EINECS

205-243-8

RTECS

US7875000

RTECS Class

Tumorigen; Drug; Mutagen; Human Data

Merck

12,7361

Beilstein/Gmelin

4924060

Beilstein Reference

2-22-00-00514

Physical and Chemical Properties

Appearance

Brick-red microcrystals with a slight violet luster or a purple powder. Aqueous solutions are yellow to brick-red and slightly acidic; they may be stabilized by the addition of 10% glucose. Slightly bitter taste.

Melting Point

138.9

Usage

Prescribed for its local analgesic effects on the urinary tract.

First Aid Measures

Ingestion

DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.

Inhalation

IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.

Skin

IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

Eyes

First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Handling and Storage

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Ingestion

See inhalation.

Inhalation

Symptoms of exposure to this compound via ingestion may include headache, rash, occasional gastrointestinal disturbances, orange to red color in the urine, hemolytic anemia, renal and hepatic toxicity, and staining of contact lenses. It may cause methemoglobinemia. It may cause gastrointestinal upset. Overdose may cause oxidative Heinz body hemolytic anemia, presence of bite cells, hemolysis, renal and hepatic impairment and occasional failure, due to hypersensitivity. Overdose may also result in hepatic enlargement, jaundice and hypersensitivity hepatitis.

Skin

See inhalation.

Eyes

See inhalation

EC Risk Phrase

R 45 22

EC Safety Phrase

S 53 45

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.

Respirators

Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter).

Poison Class

3

Fire Fighting Measures

Fire Fighting

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

If you spill this chemical, you should dampen the solid spill material with 5% acetic acid, then transfer the dampened material to a suitable container. Use absorbent paper dampened with 5% acetic acid to pick up any remaining material. Your contaminated clothing and the absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with 5% acetic acid followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Stability and Reactivity

Stability

No data.

Incompatibilities

Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents Flammable gases are formed by mixing materials in this group with alkali metals Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides.

Transport Information

UN Number

2811