Product Identification

Product Name

Troglitazone

Synonyms

2,4-Thiazolidinedione, 5-((4-((3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl) methoxy)phenyl)methyl)
5-(4-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)thiazolidine-2,4-dione
CS-045
GR-92132X
Rezulin
Romglizone

CAS

97322-87-7

Formula

C24H27NO5S

Molecular Weight

441.55

RTECS

XJ5813130

Merck

12,9898

Beilstein/Gmelin

4338399

Physical and Chemical Properties

Appearance

Yellow solid.

Solubility in water

Insoluble

Melting Point

184 - 186

Vapor Pressure

7.2E-18 (25 C)

Density

1.266 g/cm3 (20 C)

pKa/pKb

6.34 (pKa)

Partition Coefficient

4.99

Usage

An anti-diabetic and antiinflammatory drug.

Handling and Storage

Storage

This product should be stored at room temperature. It should be kept in a tightly closed container.

Hazards Identification

Inhalation

Remove from exposure. If breathing is difficult, administer oxygen. If breathing stops, administer artificial respiration. Seek medical attention immediately.

Skin

Wash with soap and water for 15 minutes. Remove contaminated clothing and shoes. Seek medical attention immediately.

Eyes

Check for and remove contact lenses. Flush eyes with running water for at least 15 minutes separating eyelids. Seek medical attention immediately.

Ingestion

Remove dentures and clear mouth. If person is conscious, rinse mouth with water. Call physician or poison control immediately.

Exposure Controls/Personal Protection

Personal Protection

For spill clean up, wear suitable protective clothing, chemical resistant rubber gloves, rubber boots, and chemical safety goggles. Self contained breathing apparatus or NIOSH/MSHA approved respirator is recommended.

Fire Fighting Measures

Fire Fighting

Extinguish with carbon dioxide, dry chemical powder, polymer foam, water spray. Use self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Wipe up spill and place in sealed container and hold for disposal. Avoid raising dust. Ventilate the area and wash spill site after material has been removed.

Stability and Reactivity

Stability

This material is stable if stored as directed.