Product Identification

Product Name

5,9-Anhydro-2,3,4,8-tetradeoxy-8-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-[2E,8[2S,3S(1S,2S)]]-L-talonon-2-enonic acid 8-carboxyoctyl ester

Synonyms

Bactroban
L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiranyl]methyl]-3-methyl-, 8-carboxyoctyl ester, (2E)-
Nonanoic acid, 9((3-methyl-1-oxo-4-(tetrahydro-3,4-dihydroxy-5-((3-(2-hydroxy-1-methylpropyl) oxiranyl)methyl)-2H-pyran-2-yl)-2-butenyl)oxy)-, (2S-(2-alpha(E),3-beta,4-beta,5- alpha(2R*,3R*(1R*,2R*))))
Pseudomonic acid A
trans-Pseudomonic acid

CAS

12650-69-0

Formula

C26H44O9

Molecular Weight

500.63

RTECS

RA6907000

Merck

12,6383

Physical and Chemical Properties

Appearance

Odorless white powder.

Solubility in water

Slightly soluble

Melting Point

77 - 78

Vapor Pressure

5.9E-21 (25 C)

Density

1.183 g/cm3 (20 C)

pKa/pKb

4.78 (pKa)

Partition Coefficient

3.44

Usage

Antibacterial.

Handling and Storage

Storage

Store cool, dark and dry.

Hazards Identification

Inhalation

Remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. Seek medical attention.

Skin

Immediately wash skin with soap and copious amounts of water for at least 15 minutes. If irritation persists, seek medical attention.

Eyes

Immediately flush eyes with copious amounts of water for at least 15 minutes. Seek medical advice.

Ingestion

If swallowed, wash out mouth with water, provided person is conscious. Seek medical advice.

EC Risk Phrase

R: 20/21/22 36/37

Exposure Controls/Personal Protection

Personal Protection

Wear self-contained breathing apparatus, rubber boots & heavy rubber gloves.

Fire Fighting Measures

Fire Fighting

Extinguish with carbon dioxide, dry chemical powder or appropriate foam. Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with the skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep-up/absorb in suitable material, place in a container and hold for disposal. Avoid raising dust. Ventilate area and wash spill site after pickup is complete.

Stability and Reactivity

Combustion Products

Emits toxic fumes under fire conditions.