Product Identification

Product Name

Dimethicone

Synonyms

(Methoxy-dimethylsilyl)-trimethylsilane
DC 1664
Dimethicone 350
Dimeticone
Dow Corning- 664
Mirasil DM 20

CAS

9006-65-9

Formula

C6H18OSi2

Molecular Weight

162.38

RTECS

IP6562500

RTECS Class

Other

Beilstein/Gmelin

NA

First Aid Measures

Ingestion

Significant toxicity is not anticipated after ingestion. Treatment is symptomatic and supportive. Consider activated charcoal only after very large ingestions. The target organs for migrating silicones have been chiefly the liver and lungs. In most cases, aggressive supportive care has been adequate to handle the immediate problem. No specific antidotes exist. No treatment is necessary for oral ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.

Inhalation

Inhalation hazard is low due to the low vapor pressure of most silicone fluids. Treatment is symptomatic and supportive.

Skin

Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.

Eyes

If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Handling and Storage

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Silicone injection has been associated with the development of fatal pulmonary edema, pneumonitis, pleural effusion, ards and dyspnea.

Skin

Hypopigmentation and peau d'orange skin changes have been reported after silicone injection or implantation.

Exposure Controls/Personal Protection

Personal Protection

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.

Respirators

Use NIOSH/MSHA approved respirator appropriate for exposure of concern.

Exposure Effects

The toxological properties of this substance have not been fully investigated.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.

Stability and Reactivity

Stability

No data.

Incompatibilities

Strong oxidizing agents.

Physical and Chemical Properties

Usage

Ointment base and topical drug ingredient skin protectant.