Product Identification

Product Name

Methacryloyl chloride

Synonyms

2-Methylprop-2-enoyl chloride
Methacrylic acid chloride
Methacrylyl chloride

CAS

920-46-7

Formula

C4H5ClO

Molecular Weight

104.54

EINECS

213-058-9

RTECS

OZ5791000

RTECS Class

Other

Beilstein/Gmelin

878175

Beilstein Reference

4-02-00-01537

Physical and Chemical Properties

Appearance

Colorless to yellow liquid.

Solubility in water

Slightly soluble

Melting Point

-60

Boiling Point

95

Vapor Pressure

44 (25 C)

Density

1.0562 g/cm3 (20 C)

Partition Coefficient

1.61

Heat Of Vaporization

33.6 kJ/mol

Usage

A hydrogel with 80% water absorption was obtained from reaction of 2-hydroxyethyl methacrylate, containing small amounts of ethylene glycol dimethacrylate with the reaction product of poly(vinylpyrrolidinone) & methacryloyl chloride contact lenses.

Refractive Index

1.4433

First Aid Measures

Ingestion

The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.

Inhalation

Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.

Skin

Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.

Eyes

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Handling and Storage

Storage

Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Refrigerator/flammables.

Handling

Wash thoroughly after handling. Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Avoid contact with heat, sparks and flame. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Ingestion

Irritation or burns of the esophagus or gastrointestinal tract may follow ingestion.

Inhalation

May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema. Causes chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema.

Skin

Dermal irritation and burning may occur. Sensitization is predicted.

Eyes

Causes severe eye burns. Lachrymator.

EC Risk Phrase

R 11 22 26 34 37

EC Safety Phrase

S 16 26 28 36/37/39 45

UN (DOT)

3286

Exposure Controls/Personal Protection

Personal Protection

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Flash Point

4

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.

Stability and Reactivity

Stability

Stable at room temperature in closed containers under normal storage.

Incompatibilities

Strong oxidizing agents.

Decomposition

Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide, chloride fumes.

Transport Information

UN Number

3286