Product Identification

Product Name

1,4-Butanedicarboxylic acid

Synonyms

1,4-Butanedicarboxylic acid
1,6-Hexanedioic acid
Acifloctin
Asapic
Hexanedioc acid
Inipol DS

CAS

124-04-9

Formula

C6H10O4

Molecular Weight

146.13999999999999

EINECS

204-673-3

RTECS

AU8400000

RTECS Class

Mutagen; Primary Irritant

Merck

13,163

Beilstein/Gmelin

1209788

Beilstein Reference

4-02-00-01956

EC Index Number

607-144-00-9

EC Class

Irritant

Physical and Chemical Properties

Appearance

Colorless or white crystalline solid. Odorless.

Solubility in water

14 g/L

Melting Point

152 - 154

Boiling Point

337

Vapor Pressure

.1

Density

1.398 g/cm3 (-143 C)

pKa/pKb

4.39 (pKa)

Partition Coefficient

.08

Heat Of Vaporization

140 kJ/mol

Heat Of Combustion

-2800 kJ/mol

Usage

Raw material for pharmaceuticals, perfume fixative.

Vapor Density

5.04

Saturation Concentration

96 ppm at 18.5 C (calculated)

Refractive Index

1.439 (20 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep away from sources of ignition. Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from strong bases.

Handling

Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Avoid mechanical shock and friction.

Hazards Identification

Inhalation

May cause respiratory tract irritation. Low hazard for usual industrial handling.

Skin

May cause skin irritation.

Eyes

May cause severe eye irritation.

Ingestion

Ingestion of large amounts may cause gastrointestinal irritation. Expected to be a low ingestion hazard.

Hazards

Melts and may decompose to give volatile acidic vapors of valeric acid and other substances. Dust may form explosive mixture with air.

EC Risk Phrase

R 36

UN (DOT)

9077

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Human effects not reported. Poisoned animals experience somnolence or seizure activity. Pregnant mice given 263 mg/kg of adipic acid from day 6 to 15 of gestation developed no negative effects on nidation, maternal or fetal survival, or fetal abnormalities.

Exposure limit(s)

TLV: 5 mg/m3(as TWA) (ACGHI 1977).

Poison Class

4

Fire Fighting Measures

Flash Point

196

Autoignition

405

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. Extinguishing media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam.

Upper exp. limit

9.6

Lower exp. limit

1.6

Fire Potential

Moderately flammable. Slight when exposed to heat or flame.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability

Stable under normal shipping and handling conditions. Dusts may form an explosion hazard.

Incompatibilities

Strong oxidizers. Corrosive to mild steel at room temperature.

Decomposition

Carbon monoxide, carbon dioxide, acrid smoke and fumes.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

9077

Hazard Class

9.2

HS Code

2917 12 10