Product Identification

Product Name

4-Amino-2-hydroxybenzoic acid phenyl ester

Synonyms

4-Amino-2-hydroxybenzoic acid phenyl ester
4-Aminosalicylic acid phenyl ester
Fenamisal
Phenyl 4-amino-3-hydroxybenzoate
Phenyl p-aminosalicylate
Pheny-PAS-Tebamin

CAS

133-11-9

Formula

C13H11NO3

Molecular Weight

229.23

EINECS

205-092-8

Merck

12,7426

Beilstein/Gmelin

2850601

Beilstein Reference

4-14-00-01979

Physical and Chemical Properties

Appearance

White.

Solubility in water

Insoluble

Melting Point

149.5 - 151

pKa/pKb

8.76 (pKa)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool, dry place. Keep container closed when not in use.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear chemical goggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

The toxicological properties of this material have not been investigated.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Irritating and toxic fumes and gases.