Product Identification

Product Name

3-Hydroxypropionitrile

Synonyms

Ethylene cyanohydrin
Hydracrylonitrile

CAS

109-78-4

Formula

C3H5NO

Molecular Weight

71.08

EINECS

203-704-8

RTECS

MU5250000

RTECS Class

Primary Irritant

Merck

13,3828

Beilstein/Gmelin

635773

Beilstein Reference

4-03-00-00708

Physical and Chemical Properties

Appearance

Clear, colorless to very slightly yellow liquid with a weak odor.

Solubility in water

Miscible

Melting Point

-46

Boiling Point

228

Vapor Pressure

0.08 (25 C)

Density

1.0588 g/cm3 (0 C)

Partition Coefficient

-.94

Usage

Solvent for certain cellulose esters and inorganic salts, organic intermediate for acrylates.

Vapor Density

2.45

Refractive Index

1.4272 (20 C)

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a cool, dry place. Keep away from water. Keep containers tightly closed.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Keep from contact with moist air and steam.

Hazards Identification

Inhalation

May cause respiratory tract irritation.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause kidney damage.

Hazards

Closed containers may rupture violently when heated. Water Reactive. Material will react with water and may release a flammable and/or toxic gas.

EC Risk Phrase

R 36/37/38

EC Safety Phrase

S 26 36

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions. Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Repeated exposure may cause kidney damage and digestive tract abnormalities.

Poison Class

4

Fire Fighting Measures

Flash Point

128

Autoignition

494

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: Water or foam may cause frothing. Do NOT get water inside containers. For large fires, use water spray, fog or alcohol-resistant foam. Cool containers with flooding quantities of water until well after fire is out. For small fires, use dry chemical or carbon dioxide.

Upper exp. limit

12.1

Lower exp. limit

2.3

Fire Potential

Flammable, combustion requires preheating quite flammable.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Do not get water on spilled substances or inside containers.

Stability and Reactivity

Disposal Code

6

Incompatibilities

Acids, bases, strong oxidizing agents, moisture.

Stability

Stable under normal temperatures and pressures.

Decomposition

Hydrogen cyanide, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Combustion Products

Toxic gases are generated when heated.

Transport Information

HS Code

2926 90 95