Product Identification

Product Name

8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline diphosphate

Synonyms

1,4-Pentanediamine, N(sup 4)-(6-methoxy-8-quinolinyl)-, phosphate (1:2)
8-((4-Amino-1-methylbutyl)amino)-6-methoxyquinoline diphosphate
N-(6-Methoxyquinolin-8-yl)pentane-1,4-diamine phosphoric acid
Primachin
Quinoline, 8-((4-amino-1-methylbutyl)amino)-6-methoxy-, phosphate (1:2)

CAS

63-45-6

Formula

C15H27N3O9P2

Molecular Weight

455.34

EINECS

200-560-8

RTECS

VA9660000

RTECS Class

Drug; Mutagen; Reproductive Effector

Beilstein/Gmelin

3812133

Beilstein Reference

5-22-12-00127

Physical and Chemical Properties

Appearance

Orange.

Melting Point

197 - 198

Heat Of Vaporization

Usage

Antimalarial agent.

First Aid Measures

Ingestion

Do NOT induce vomiting. Allow the victim to rinse his mouth and then to drink 2-4 cupfuls of water, and seek medical advice.

Inhalation

Remove from exposure to fresh air immediately.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Immediately flush with running water for at least 20 minutes.

Handling and Storage

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Ingestion

See Inhalation.

Inhalation

TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Effects of contact or inhalation may be delayed.

Skin

Contact with molten substance may cause severe burns to skin and eyes. See Inhalation.

Eyes

See Inhalation.

Hazards

Contact with metals may evolve flammable hydrogen gas.

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Wear appropriate protective gloves, clothing and goggles.

Respirators

Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.

Fire Fighting Measures

Fire Fighting

Extinguish using agent most appropriate for surrounding fire.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Sweep up, then place into a suitable container for disposal.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Nitrogen oxides, phosphine, carbon monoxide, carbon dioxide, nitrogen.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2811

Hazard Class

6.1

Packing Group

I; II; III