Product Identification

Product Name

1-(4-Hydroxyphenyl)-2-(methylamino)ethanol

Synonyms

(+/-)-N-Methyloctopamine
1-(4-Hydroxyphenyl)-2-methylaminoethanol
4-Hydroxy-a-(methylaminomethyl)benzyl alcohol
b-Methylamino-a-(4-hydroxyphenyl)ethyl alcohol
p-Hydroxy-a-[(methylamino)methyl]benzyl alcohol

CAS

94-07-5

Formula

C9H13NO2

Molecular Weight

167.21

EINECS

202-300-9

RTECS

DO7350000

RTECS Class

Drug

Merck

13,9104

Beilstein/Gmelin

1103010

Beilstein Reference

2-13-00-00491

Physical and Chemical Properties

Solubility in water

Very soluble

Melting Point

187

Boiling Point

341

Vapor Pressure

3E-5 (25 C)

pKa/pKb

4.63 (pKb)

Heat Of Vaporization

61.7 kJ/mol

Usage

A-adrenoceptor agonist, vasoconstrictor.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water.

Eyes

In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Handling and Storage

Storage

Keep tightly closed. Store at 2-8 C

Hazards Identification

Inhalation

Material is irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.

Skin

Causes skin irritation. May be harmful if absorbed through the skin.

Eyes

Causes eye irritation.

Ingestion

May be harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

36/37/38

EC Safety Phrase

26 36

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles.

Respirators

Government approved respirator.

Exposure Effects

Irritant. Irritating to eyes, respiratory system and skin.

Fire Fighting Measures

Flash Point

163

Fire Fighting

Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides.