Product Identification

Product Name

4-Methyl-1-oxa-4-azacyclohexane

Synonyms

4-Methyl-1-oxa-4-azacyclohexane
N-Methyl morpholine

CAS

109-02-4

Formula

C5H11NO

Molecular Weight

101.15

EINECS

203-640-0

RTECS

QE5775000

RTECS Class

Reproductive Effector; Primary Irritant

Beilstein/Gmelin

102719

Beilstein Reference

4-27-00-00020

EC Class

highly flammable, harmful, corrosive

Physical and Chemical Properties

Appearance

Clear, colorless liquid with a strong ammonia-like odor.

Solubility in water

Soluble

Melting Point

-66

Boiling Point

115

Vapor Pressure

10 (12 C)

Density

0.922 g/cm3 (20 C)

pKa/pKb

7.38(at 25℃) (pKa)

Partition Coefficient

-.16

Heat Of Vaporization

39.6 kJ/mol

Heat Of Combustion

-3344 kJ/mol

Usage

Laboratory use. Catalyst. Reaction of phenyl isothiocyanate and diphenylphosphinic hydrazide.

Vapor Density

3.5

Refractive Index

1.4332 (20 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure. Destroy contaminated shoes.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Handling and Storage

Storage

Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Follow all MSDS and label precautions even after container is emptied because they may contain product residues. Use spark-proof tools and explosion proof equipment. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid ingestion and inhalation. Do not ingest or inhale. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Inhalation

Causes respiratory tract irritation. Irritation may lead to chemical pneumonitis and pulmonary edema.

Skin

Causes skin irritation. May be absorbed through the skin in harmful amounts. May cause skin burns.

Eyes

Causes moderate eye irritation. May cause eye burns. May cause conjunctivitis.

Ingestion

Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.

Hazards

May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

EC Risk Phrase

R 11 20/21/22 34

EC Safety Phrase

S 16 26 36/37/39 45

UN (DOT)

2535

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Prolonged or repeated skin contact may cause defatting and dermatitis.

Exposure limit(s)

OEL-RUSSIA:STEL 5 mg/m3;Skin

Poison Class

4

Fire Fighting Measures

Flash Point

12

Autoignition

165

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Can release vapors that form explosive mixtures at temperatures above the flashpoint. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Use water spray to cool fire-exposed containers. In case of fire use water spray, dry chemical, carbon dioxide, or chemical foam. Cool containers with flooding quantities of water until well after fire is out.

Upper exp. limit

11.8

Lower exp. limit

2.2

Fire Potential

Flammable/combustible material.

Accidental Release Measures

Small spills/leaks

Use water spray to dilute spill to a non-flammable mixture. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Scoop up with a nonsparking tool, then place into a suitable container for disposal. Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Provide ventilation.

Stability and Reactivity

Disposal Code

1

Incompatibilities

Acids, acid chlorides, acid anhydrides, carbon dioxide, strong oxidizing agents.

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide.

Combustion Products

Fire will produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2535

Hazard Class

3

Packing Group

II

HS Code

2934 99 90