Product Identification

Product Name

Ethisterone

Synonyms

17a-Ethynyltestosterone
17b-Hydroxy-4,17a-pregnen-20-yn-3-one
4,17a-Pregnen-17b-ol-20-yn-3-one
Anhydrohydroxyprogesterone
Ethynyltestosterone
Progestoral

CAS

434-03-7

Formula

C21H28O2

Molecular Weight

312.45

EINECS

207-096-5

RTECS

TU5570250

RTECS Class

Reproductive Effector; Human Data; Hormone

Merck

12,3787

Beilstein/Gmelin

1889895

Beilstein Reference

4-08-00-01225

Physical and Chemical Properties

Appearance

White crystalline powder

Solubility in water

Soluble.

Melting Point

201 - 205

Boiling Point

446

Vapor Pressure

8E-10 (25 C)

pKa/pKb

13.11 (pKa)

Heat Of Vaporization

81.3 kJ/mol

Usage

A testosterone derivative with effects similar to progestational.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water.

Eyes

In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Handling and Storage

Storage

Keep tightly closed. Store in a cool dry place.

Hazards Identification

Inhalation

TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Effects of contact or inhalation may be delayed.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Ingestion

See Inhalation.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

40 48

EC Safety Phrase

22 24/25

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.

Respirators

Wear positive pressure self-contained breathing apparatus (SCBA).

Exposure Effects

Toxic. Harmful by inhalation, in contact with skin and if swallowed. May cause harm to the unborn child. Target organ(s): Female reproductive system. Nerves.

Fire Fighting Measures

Flash Point

190

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2811

Hazard Class

6.1