Product Identification

Product Name

2-(Hydroxyethyl)trimethylammonium bitartrate

Synonyms

2-Hydroxyethyl-trimethylazanium (2R,3R)-2,3,4-trihydroxy-4-oxobutanoate
Choline bitartrate
Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with [R-(R*,R*)]-2,3-dihydroxybutanedioic acid (1:1)
Strontium dihydroxide

CAS

18480-07-4

CAS

87-67-2

Formula

C9H19NO7

Formula

H2O2Sr

Molecular Weight

253.25

Molecular Weight

265.75

EINECS

201-763-4

EINECS

242-367-1

RTECS

WK9100000

RTECS Class

Reproductive Effector

Merck

12,9004

Beilstein/Gmelin

39904 (G)

Beilstein/Gmelin

4064889

Physical and Chemical Properties

Appearance

colorless orthorhombic crystals, hygroscopic

Appearance

Free flowing, white crystalline powder.

Solubility in water

10 g/L (25 C)

Melting Point

150

Melting Point

375

Density

1.47 g/cm3

Usage

Medication.

Usage

Refining beet sugar.

First Aid Measures

Ingestion

Induction of vomiting is usually not necessary due to spontaneous vomiting. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Bethanechol - for substantial ingestions of bethanechol, consider gastric lavage preceded by endotracheal intubation. Other agents - carbachol, acetylcholine, and pilocarpine are liquids, rapidly absorbed and probably not removed significantly by gastric emptying procedures. Atropine sulfate is the drug of choice. For significant muscarinic symptoms administer: adults - 2 to 4 mg iv, repeated every 3 to 60 minutes as needed to control symptoms, then prn for 24 to 48 hours. Child - 0.04 To 0.08 Mg/kg iv (up to 4 mg) repeated every 5 to 60 minutes as necessary. Epinephrine - may assist in overcoming severe cardiovascular or bronchoconstrictor responses (dose: 0.1 To 1.0 Mg sc).

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.

Inhalation

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.

Inhalation

Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Can produce delayed pulmonary edema.

Skin

Causes skin irritation.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Skin

Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Eyes

Causes eye irritation. May cause chemical conjunctivitis.

Eyes

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Handling and Storage

Storage

Keep tightly closed in a cool place in a tightly closed container.

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Handling

Containers of this material may be hazardous when emptied. Since emptied containers retain product residues (vapor, liquid, and/or solid), all hazard precautions given in the data sheet must be observed.

Hazards Identification

Ingestion

Nausea, vomiting, abdominal pain, diarrhea, or belching may be noted.

Inhalation

Dyspnea, bronchospasm, tachypnea, increased bronchial secretions, and pulmonary edema may occur, especially in asthmatic patients.

Skin

Unlikely to cause skin irritation or injury

Eyes

Dust can cause eye irritation. Symptoms include stinging, tearing, redness, and swelling of eyes.

Hazards

Dusts can form explosive mixtures in air.

Exposure Controls/Personal Protection

Personal Protection

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Respirators

3M Dust respirator No. 8710 or 9900 is recommended or a NIOSH/MSHA jointly approved dust respirator.

Exposure Effects

Effects may be delayed.

Poison Class

4

Fire Fighting Measures

Fire Fighting

Extinguish fire using regular foam, water fog, carbon dioxide, sand. Wear a self-contained breathing apparatus with a full facepiece operated in the positive pressure demand mode with appropriate turn-out gear and chemical resistant personal protective equipment.

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Small spills/leaks

Small Spill - Sweep up material for disposal or recovery. Large Spill - Shovel material into containers. Thoroughly sweep area of spill to clean up any residual material.

Stability and Reactivity

Incompatibilities

Oxidizing agents.

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Stability

Stable.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Decomposition

Oxides of carbon.