Product Identification

Product Name

(2R-cis)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone

Synonyms

(-)-BCH 189
2(1H)-Pyrimidinone, 4-amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)
2(1H)-Pyrimidinone, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, (2R-cis)
Epivir
Hepitec
Heptivir

CAS

134678-17-4

Formula

C8H11N3O3S

Molecular Weight

229.26

RTECS

UW7361333

RTECS Class

Drug; Reproductive Effector

Merck

12,5365

Beilstein/Gmelin

5480511

Beilstein Reference

6-25

Physical and Chemical Properties

Solubility in water

Soluble

Melting Point

178

Boiling Point

475

Vapor Pressure

5E-11 (25 C)

Density

1.503 g/cm3

pKa/pKb

9.59 (pKb)

Heat Of Vaporization

85.2 kJ/mol

Usage

Anti-retroviral agent- a nucleoside reverse transcripts inhibitor.

Fire Fighting Measures

Flash Point

241

Exposure Controls/Personal Protection

Exposure Effects

Properties of this material have not yet been prepared. Any recommendations are of a general nature. Many chemicals cause irritation of the eyes, skin, and respiratory tract. In severe cases respiratory tract irritation can progress to ARDS/acute lung injury which may be delayed in onset for up to 24 to 72 hours in some cases Irritation or burns of the esophagus or gastrointestinal tract are also possible if caustic or irritant chemicals are ingested. ALWAYS contact your local poision control authority or medical professional for assistance.